Esterase-like activity of human serum albumin: Structure-activity relationships for the reactions with phenyl acetates and p-nitrophenyl esters.
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Esterase-like activity of human serum albumin toward prodrug esters of nicotinic acid.
The esterase-like activity of human serum albumin (HSA) toward esters of nicotinic acid was investigated under a variety of conditions such as protein concentration, temperature, pH, ionic strength, nature of buffers, and presence of organic solvents. Initial rate constants of hydrolysis of 18 nicotinates in the presence of 50 microM HSA were measured at pH 7.4 and 37 degrees C. The substrates ...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1979
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.27.2781